A new generation of predictive computational model of the skin epidermis designed to characterize the impact of a cosmetic, drug and other environmental and intrinsic factors on the skin biology.

ABOUT SISMAAT

Sismaat™ is a new generation of predictive computational model of the skin epidermis assisting cosmetic and pharmaceutical companies to develop better and safer products/drugs and allowing consumers to benefit from personalized tool to predict the impact of a cosmetic or a drug on his own skin. The renewal of the human epidermis is a complex and multistage process that involves cell proliferation, differentiation, apoptosis, migration and desquamation. Sismaat provides a stochastic simulation integrated with an agent-based cell migration model designed to simulate and visualize the spatial-temporal dynamics of the epidermal renewal at various conditions. ....More

HOW IT WORKS

1 CONFIGURE SIMULATION

Configuring simulation parameters is very handy . All parameters are explained with fields.
For your convenience, default values already given with each parameters.

Set Population, duration etc
Configure 2D and 3D output
Advanced settings on cells

RUN SIMULATION 2

After setting all the parameters, you are ready to run the simulation by hitting
"Run Simulation" button

3 CHECK YOUR SIMULATIONS

All your simulations are saved in "My Simulations List". You can re-run the simulation, view parameters and download the simulation anytime.

4 DOWNLOAD AND RUN SIMULATION VIDEO

Once the system finished the simulation, you will be notified and you can download the simulation file on your computer.



SISMAAT RESEARCH

Psoriasis models.
PSORIASIS MODELS
Epidermal lineage: modeling of the lineage of single parent cells and their daughter cells. Significance of the modeled vs biological data.
EPIDERMAL LINEAGE
Cell lifetime modeling, turnover of epidermal layers, stem cells, stratification.
CELL TIME MODELING
Difference in striation, turnover of cell and types, factors of structure differences of the skin.
DIFFERENCE IN STRIATION

CONFERENCES AND PUBLICATIONS

PARTNERING WITH SISMAAT

SISMAAT provides an open discovery platform for academic and private partners that are interested in developing advanced predictive model for skin applications. If you are interested in learning more about our partnering programs, please contact us using the form below.

SPRIM is an integrated, global health centered consulting firm, with practice areas that include Strategy and Innovation, Regulatory and Scientific Affairs, Research & Clinical Services, all designed to help companies, academia and governments accelerating health innovation.


The CAS-MPG Partner Institute was founded on May 2005. It was jointly established by Chinese Academy of Sciences (CAS) and German Max Planck Society (MPG). The new institute will focus its research on the interface between theoretical and experimental molecular and cell biology.

LVMH Recherche is the common international research center of all the perfumes and cosmetics brands of the LVMH group, Moët Hennessy - Louis Vuitton. LVMH Recherche was founded in 1981 as a G.I.E. (Groupement d’Intérêt Economique). ....More

CONTACT US

Request for an Access or Know more about SISMAAT

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